PHOSPHODIESTERASE I
phosphodiesterase I type vii from crotalus atrox
CAS: 9025-82-5
Molecular Formula:
PHOSPHODIESTERASE I - Names and Identifiers
PHOSPHODIESTERASE I - Physico-chemical Properties
| Appearance | Morphological crude dried venom |
| Storage Condition | -20°C |
| MDL | MFCD00131883 |
| Use | Overview phosphodiesterases (PDEs) are a class of enzymes that hydrolyze the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), involved in a variety of signal transduction and physiological activities. PDEs is composed of 21 genes, which are divided into 11 families (PDE1 ~ 11) according to their sensitivity to inhibitors and amino acid sequence. The diversity of PDE family genes and their complex expression patterns suggest that different subtypes may have different pathological and physiological mechanisms. PDEs is involved in the occurrence and development of inflammation, asthma, depression and other diseases, and can be used as an important target for the treatment of various complex diseases. Therefore, the discovery of PDEs inhibitor lead compounds including synthetic and natural sources is the key to promote the development of new drugs for such inhibitors. |
PHOSPHODIESTERASE I - Risk and Safety
| Hazard Symbols | T+ - Very toxic |
| Risk Codes | 26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | SZ5999500 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
PHOSPHODIESTERASE I - Upstream Downstream Industry
| Downstream Products | 6-Thioguanine Disodium 5-Inosinate Adenosine 5-monophosphate Deoxynucleotide |
PHOSPHODIESTERASE I - Reference
| Reference Show more | 1. Chai Yangyang, Wang Yuxuan, Ai Kai, etc. Study on the extraction of tea tree mushroom flavor substances and flavor [J]. Chinese condiment, 2020, v.45;No.493(03):8-13 17. 2. Liu Zichen et al. [IF = 2.629]. "Rapid Screening of Potential phosphosterase Inhibitors from the Roots of Ilex pubescens Hook. et Arn. Using a Combination of Ultrafiltration and LC-MS."Evid-Based Compl Alt. 2017;2017:2749643 3. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 |
PHOSPHODIESTERASE I - Vitality definition
One Unit hydrolyzes one micromole of p-nitrophenyl thymidine-5-phosphate per minute at 25℃, pH 8.9.
Last Update：2023-08-16 21:32:38
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tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: Phosphodiesterase Visit Supplier Webpage Request for quotationCAS: 9025-82-5
Tel: +86-400-900-4166
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View History
PHOSPHODIESTERASE I
DIADENOSINE PENTAPHOSPHATE AMMONIUM SALT
Modifiers
MAGNESIUM PHOSPHATE, TRIBASIC PENTAHYDRATE
HEXAETHYLPHOSPHOROUS TRIAMIDE
BIS(DIMETHYLAMINO)PHOSPHINOUS CHLORIDE
DIADENOSINE PENTAPHOSPHATE AMMONIUM SALT
Modifiers
MAGNESIUM PHOSPHATE, TRIBASIC PENTAHYDRATE
HEXAETHYLPHOSPHOROUS TRIAMIDE
BIS(DIMETHYLAMINO)PHOSPHINOUS CHLORIDE
Downstream Products for PHOSPHODIESTERASE I